He served as professor of immunology at St. Marys Hospital Medical School, London, until 1967, when he joined the faculty at the University of Oxford. Porter approached the problem of antibody structure by using an enzyme, papain, to cleave the bloods immunoglobulin molecule into functionally different fragments, which were then amenable to structural analysis. Edelman, working independently, used different methods to break up the molecule, and concluded that rather than a single chain of amino acids, it was a multichain entity. Porter and his research team were then able to…
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